CovidV1, Main, Exploration, bibRecord, 001686

CHRONIC ENCEPHALOMYELITIS WITH SPECIFIC INCREASE IN INTRATHECAL MUMPS ANTIBODIES

Identifieur interne : 001686 ( Main/Exploration ); précédent : 001685; suivant : 001687

CHRONIC ENCEPHALOMYELITIS WITH SPECIFIC INCREASE IN INTRATHECAL MUMPS ANTIBODIES

Auteurs : Antti Vaheri [Finlande] ; Ilkka Julkunen [Finlande] ; Marja-Leena Koskiniemi [Finlande]

Source :

The Lancet [ 0140-6736 ] ; 1982.

RBID : ISTEX:79E24744BB9DB8750D760A50C64896A62FF66760

English descriptors

Teeft :
- Antibody, Antibody patterns, Antibody production, Antibody ratio, Antibody response, Aqueductal stenosis, Bactericidal activity, Cerebrospinal fluid, Chlamydia group antigen, Chronic encephalomyelitis, Chronic infections, Clin microbiol, Control patients, Enzyme immunoassay, Further deterioration, Fusion protein, Measles, Measles virus, Multiple sclerosis, Mumps, Mumps antibodies, Mumps meningitis, Mumps virus, Mumps virus infection, Mycoplasma pneumoniae, Neuropsychological deficiences, Normal range, Oligoclonal, Outpatient clinic, Panencephalitis, Positive babinski sign, Present case, Protein concentration, Pseudomonas, Respiratory syncytial, Rubella, Sclerosing, Serum mumps, Sick children, Specific increase, Structural proteins, Subacute, Subacute sclerosing panencephalitis, Toxoplasma gondii, Virus.

Abstract

Abstract: Symptoms of severe encephalomyelitis developed in a 31-year-old man in 1967. He had a high serum antibody titre to mumps virus associated with a polymorphic cell reaction and an increased protein concentration in cerebrospinal fluid (CSF). He recovered considerably within a year and was able to resume work. In 1975 his condition deteriorated again; it improved during the following few years, but a further deterioration then occurred. In March, 1981, the complement-fixing antibody titre to mumps virus was 1/32 in the serum and 1/4 in the CSF. In November, 1981, the CSF IgG index was increased and the altered serum/CSF antibody ratio persisted. The specificity of the altered antibody ratio was confirmed by the single radial haemolysis test and an immunoassay specific for mumps virus. Antibodies against the mumps virus envelope glycoprotein, M-protein, and nucleoprotein could be demonstrated by immunoprecipitation and the antibody patterns in serum and CSF were similar. Antibodies against other microorganisms were not detected in the patient's CSF, and mumps antibodies were not found in the CSF specimens of 57 control patients. This case may be an example of a new disease—chronic mumps virus infection in the central nervous system.

Url:

https://api.istex.fr/ark:/67375/6H6-SBV3F0H3-1/fulltext.pdf

DOI: 10.1016/S0140-6736(82)90713-9

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 000536
to stream Istex, to step Curation: 000516
to stream Istex, to step Checkpoint: 000802
to stream Main, to step Merge: 001715
to stream Main, to step Curation: 001686

Le document en format XML

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<term>Antibody response</term>
<term>Aqueductal stenosis</term>
<term>Bactericidal activity</term>
<term>Cerebrospinal fluid</term>
<term>Chlamydia group antigen</term>
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<term>Chronic infections</term>
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<term>Respiratory syncytial</term>
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<term>Sclerosing</term>
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<term>Sick children</term>
<term>Specific increase</term>
<term>Structural proteins</term>
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<front><div type="abstract" xml:lang="en">Abstract: Symptoms of severe encephalomyelitis developed in a 31-year-old man in 1967. He had a high serum antibody titre to mumps virus associated with a polymorphic cell reaction and an increased protein concentration in cerebrospinal fluid (CSF). He recovered considerably within a year and was able to resume work. In 1975 his condition deteriorated again; it improved during the following few years, but a further deterioration then occurred. In March, 1981, the complement-fixing antibody titre to mumps virus was 1/32 in the serum and 1/4 in the CSF. In November, 1981, the CSF IgG index was increased and the altered serum/CSF antibody ratio persisted. The specificity of the altered antibody ratio was confirmed by the single radial haemolysis test and an immunoassay specific for mumps virus. Antibodies against the mumps virus envelope glycoprotein, M-protein, and nucleoprotein could be demonstrated by immunoprecipitation and the antibody patterns in serum and CSF were similar. Antibodies against other microorganisms were not detected in the patient's CSF, and mumps antibodies were not found in the CSF specimens of 57 control patients. This case may be an example of a new disease—chronic mumps virus infection in the central nervous system.</div>
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CHRONIC ENCEPHALOMYELITIS WITH SPECIFIC INCREASE IN INTRATHECAL MUMPS ANTIBODIES

CHRONIC ENCEPHALOMYELITIS WITH SPECIFIC INCREASE IN INTRATHECAL MUMPS ANTIBODIES

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri